Projects

Lead: Rachel Knevel, Dept of Rheumatology LUMC, the Netherlands

Our role: Project lead

Aim: Aim: SPIDeRR aims to disentangle the real-life complexity of early diagnosis of rheumatic diseases by considering the complete web of factors influencing patients’ symptoms. It will deliver: -a symptom checker for patients, -a decision support tool for (primary) care providers providing guiding additional examination and referral decisions -a patient-patient similarity network to optimise diagnostic groups in rheumatology and support treatment decision

Lead: Lars Klareskog, Dept of Rheumatology Karolinska Institute Zweden

Our role: Implementation

Aim: DigiPrevent enables personalised prevention in RA, combined with much earlier treatment if arthritis ensues, through a new digital screening procedure, Rheumatic and a blood based diagnostic tool, Rheuma-multiplex.

Lead: Daniel Aletaha, Dept of Rheumatology, Vienna

Our role: Analytic lead

Aim: SQUEEZE integrates to validate clinical, laboratory, molecular, digital and behavioural biomarkers to enable the recognition of patients with high likelihood of response to treatment and the selection of the drug with highest chance of benefit for an individual patient; and as such improve efficacy and safety of existing therapies (by squeezing the most out of existing drugs) in synergy with other EU-wide activities

Lead: Lars Klareskog, Dept of Rheumatology Karolinska Institute Zweden

Our role: Bioinformatic lead

Aim: Prevent RA or its progression by inhibiting the expansion of pathogenic autoimmune responses through immune tolerising treatments.